I run an AxeFX Ultra for pretty much everything, after a bunch of tours with a 6505+ head, 4x12 and a 6u rack case full of effects, I decided to downsize and haven't regretted it. My back's even happier!
I'm not a fan of having to step on things on stage either, I've run pedalboards before but often I'd get too into the performance and be lead's length away when it's tapdance time.
The added bonus of having patch changes automated and synchronised with a backing/click track was a big plus too. One cable between my guitar and the Fractal, just how I like it.