You must consider them along with the rest, as the final result is the sum of all the parts. Another consideration is boundary cancellations, which occur when the distance from the speaker to a boundary is 1/4 wavelength, and/or when the difference in the distance from the speaker to a boundary to the listener totals 1/2 wavelength. These cancellations typically are manifested relatively close to the speaker, which is to say on the stage. They diminish as you get further away. It's why your on stage sound can seem bass weak while it's too much in the audience. It's the source of the myth of wave propagation, the notion that one must be a certain distance from the source for a low frequency wave for the dB level to reach its full potential. Accounting for it and the rest is why you need to do a sound check standing where it matters most, in the audience, or as close to it as possible, when setting your EQ. As often as not perfect tone on stage can be boomy out front.