[quote name='hairychris' timestamp='1450269918' post='2931184']
Having spent a lot of time in 2 guitar bands as a guitarist, I always found the guitars sit better with one more mid-focused, and the other slightly scooped. Note: slightly, as in just for emphasis, and preferably following the amp's strengths (Marshall JCM800 and Mesa Dual Rectifier is a fantastic combination, for example).
[/quote]
This. My main band has a one guitarist into a JCM800 head, into a full-sized 4x12" cab with a scooped tone, and another guitarist with a Peavey ValveKing MkII head into a 4x12" extension cab (smaller enclosure) with a lot more mids. They work really well together, and there's [i]just[/i] enough room for me to poke through with a dirty/clanky jazz bass. Took us a while to find what worked though, so if your guitarist is prepared to listen to suggestions bear in mind that it might take a couple of rehearsals (and even gigs) to find the solution.