2 of the rooms I play in couldn't be more different. The first one is nice sounding, high and sharply pitched ceiling, lots of stuff on the walls. Sounds great. Small amount of natural reverb.
Then the other - no matter what EQ, no matter what other instruments it just sounds horrible. Somehow boomy and dead at the same time. I end up lowering the bass and low mids massively and getting a twangy sound just so I can then turn it up enough to hear it without the room going boooooooooooooom.
Doesn't help that the supplied drum kit has the longest kick drum I've ever heard. But will they put a pillow in it...