Welcome to the forum John.
The way I see it, if a neck was manufactured with the correct amount of relief built in, then I'd be happy to do all action adjustments on the bridge. To me, changing relief is just a means of counteracting neck movements due to string changes - getting rid of the associated buzz, not adjusting action. If a neck never moved, regardless of string type, then a good bridge should be all you need to adjust action.
You'd need to be pretty damned sure that it will never move though!
Good luck with the project.