Couple things I'd check first.
Kept the gain low and use the master volume to avoid distortion, as those buttons will increase certain frequencies and push the preamp.
Second, is get some contact cleaner and spray it into the gap around the button while pressing each one in and out about 20-30 times to loosen any dirt that may be affecting the signal.
Third, do the same with the contact cleaner on the volume controls while twiddling them to again remove any debris.
Question, what are you settings when this happens, or does it happen at any volume?