The OP mentions the Crate Powerblock.
I use one of these for everything.
In my office, I have a small mixer - this has a couple of mikes running into the XLRs, a guitar into a Digitech Genesis into channel 3, a bass into an MXR-80+ into 4 and a Zoom 123 drum machine into 5.
My laptop is connected into the back via phonos and the desk is connected into it via two 1/4" jacks. Two 30W 16 Ohm speakers are run from it as monitors, plus my headphones come off the desk. The amp gives roughly 30W per side set up like this.
Add to this I take it to rehersals through a 12" Ampeg Walkabout with a Beyma speaker, using the MXR-80+ as the pre, giving 150W bridged.
I can also hook the Genesis into it & use it for guitar.
I've even used it as a small PA.
I believe these were £299 when they were first intoduced and when Sound Control blitzed them at £50 each I decided I couldn't miss out.
The only peeve I have with it is that there is a constant 'crunch' underlying it even when set up very clean.
G.