Taped fingers changes the sound, but that's not an issue for practicing.
I used to get blisters, but no longer do and I don't think my right hand is significantly more calloused than it was. Some things I've learned over 30 odd years:
Let the amp take the strain, you don't need to pluck that hard.
Share the load, use index and middle finger. I used to use just my middle finger but now use both, some sequences of notes fall easier if you alternate between fingers.
Play little and often if you can, building up to those three hour gigs!
Pluck diagonally across the strings, it sounds better and spreads the load across more skin.
Some people recommend wiping your finger down the side of your nose to apply a little natural lubricant. Sounds a bit gross, but works actually.
Keep playing!