DIfficult... for me at least, but I would go with an Octaver (EBS Octabass or Aguilar Octamizer) and some dirt (Phat Phuk B, B3K, Awesome Fuzz Machine...).
I would be missing some modulated delay though... so many different sounds you can get out of one of those.
I had a Nano loaded with a JHS buffer, Aguilar Octamizer, Fuzzrocious Rat Tail (smaller enclosure), Line M5, small controller for the M5 and a TC Ditto looper and that was an amazing travelling board. So compact and versatile.