I found that each bass ended up sounding best with very different settings (as it looks like you are, too)
On the whole, I didn't use the cab modelling other than for special sounds.
My main setup was:
Vigier 4 fretted - 'adam and eve' head with a touch of EQ, reverb, compression (loved the compressor in the XT)
Vigier 4 fretless - 'SM500 head and EA 1x12 cab, reverb, chorus (switchable) and eq, comp
Vigier 5 fretted - 'Eighties' head, reverb, compression
...And a couple of 'specials' - stink synth being a fave which had all sorts going on.
Through my amplifier at the time (Trace V4) I bypasses all modelling but used a touch of compression and reverb.
I really loved my XT pro and even though the route to finding the right tones was long and fiddly, when i had then dialled, it was a great plug and play unit, it worked in the studio, live and at home, and my basses sounded like themselves without any messing about.
Now I use the Roland Vbass which is arguably harder to use but I still have the same sound through everything as I did with the pod. I guess I wanted the most 'honest' sound for each bass and mainly used it as an audio interface and compressor.
Here are my settings if you want to mess about with them:
[url="http://dl-client.getdropbox.com/u/85432/line6%20patches/Stink%20synth.l6t"]http://dl-client.getdropbox.com/u/85432/li...ink%20synth.l6t[/url]
[url="http://dl-client.getdropbox.com/u/85432/line6%20patches/Stink%20wop.l6t"]http://dl-client.getdropbox.com/u/85432/li...Stink%20wop.l6t[/url]
[url="http://dl-client.getdropbox.com/u/85432/line6%20patches/SVT%20grit.l6t"]http://dl-client.getdropbox.com/u/85432/li.../SVT%20grit.l6t[/url]
[url="http://dl-client.getdropbox.com/u/85432/line6%20patches/Vigier%20Studio%204.l6t"]http://dl-client.getdropbox.com/u/85432/li...0Studio%204.l6t[/url]
[url="http://dl-client.getdropbox.com/u/85432/line6%20patches/Vigier%20Studio%20FL.l6t"]http://dl-client.getdropbox.com/u/85432/li...Studio%20FL.l6t[/url]
Cheers
ped
P.s some samples of the sounds being used (just to show how bass specific they are - they will probably sound totally different on your bass)
[url="http://www.freewebs.com/mrped/facethemusic.htm"]http://www.freewebs.com/mrped/facethemusic.htm[/url]
(Torrential - fretless setting)
(2001 - stink synth)
[url="http://www.freewebs.com/mrped/apps/videos/videos/view/939477-vigier-guitars-demo"]http://www.freewebs.com/mrped/apps/videos/...er-guitars-demo[/url]
(Vigier fretted 4 setting, fretless setting and 5 string setting)