I went with Cubase, simply because it's what I used many years ago on the Atari ST, and it's a doddle.
If that's the way it's going to be, it might be worth looking at one of the Steinberg interfaces. I've had both the UR12 and now have the UR22 so we can put tracks down together. The Yamaha pre that they use is great, and I've never had a moment's trouble with either, just plug in and play.
The reason I'm suggesting this is because they come bundled with Cubase AI, which I ran for about 2 years without feeling unneccesarily restricted. I did eventually upgrade to Elements, but only because they kept sending me better and better offers to do so (it cost me 25 quid in the end, as an upgrade from the bundled version, so I saved a fair bit compared to buying it). There are a few more VSTs, but from a day to day use point of view it strikes me as barely different, based on the features I commonly use.