there are no other basses that have all the features of my custom Shukers, so yes it does matter for me.
Does it matter for the punters? I think so, they may not know why 'Everybody Wants to Rule the World' doesn't sound as good played on a normal 4 string - no drop D - but they will notice.
Same as the metal solo's I needed a 2 octave neck for. The punters will hear the difference if they are played an octave lower.