One cab per channel @ 8Ω gives you 720W with the input switched to parallel. This is how I operate my system.
Running your power amp in bridge releases a vast amount of power which will, in the end, toast your speaker cabinets.
Another related point is that a 1x15 will not handle the power that a 4x10 is able to. In use. if you must use this match up, stack the 4x10 in the bottom position so you can more easily hear the cries of pain from the 15.
Thinking that a 15 will produce more lows is wrong. The close coupled four tens will be more capable of doing that and will have greater sensitivity.
Just as a question: is the Cavern still active, pandemic aside? I played there in the sixties. LOL