Depends on the speaker and the volume level.
You can plug a sim in and play through a FRFR cab and get the desired tone at low stage volume, although in that case it likely wouldn't be mic'd, but the idea holds for home use and recording, without a sim you won't get the A-Z tones out of the FRFR cab and you're stuck with the tones of any other cab at the volume level you can have.