Hi Kevin,
we used it with a pair of Mackie subs, but that was through the full range outputs, as the high/low pass filtering is done by the Mackies.
however, there are low pass filters built in, and several different outputs, so looks like it's possible to configure a low pass ,sub out.
now, I'm no expert on mixers, but Whizzy may have a more definitive answer for you .
full manual comes with the mixer !
mike.